বৃহস্পতিবার, ২৮ মার্চ, ২০১৩

AP Photos: Washington island landslide (Providence Journal)

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Same-sex couple leaves the US because of DOMA



>>> let me bring in brandon pearlburg. an american living in london with his foreign-born partner. the couple had to move in order to stay together because of doma . thank you for joining me.

>> thank you.

>> first of all, what is your impression of today. with the excerpts and analysis coming out regarding justices and their comments, brandon ?

>> well, i don't want it make any predecks, but we know every time in our country's history that there's been an expansion of civil rights , that has been a good thing for the population as a whole, and those have been moments that we look back upon with tremendous national pride . so i guess i would say i'm cautiously opt moistic that this is going to to be another one of those moments.

>> you mentioned national pride . you are an american citizen . you love this country. as i read, nearly seven years ago you decided you could no longer live here based on love, if you will. tell me a little bit about what happened and how you made this decision to leave your home and go to london .

>> well, what happened for me was that in the fall of 2011 , i had been with my same sex british partner for just about seven years then. we've been together another year now. and he was living in the states with me pursuant to an employer sponsored visa. but those visas have expiration date . the way you stay in the country is with a green card . he wasn't going to to get a green ward from his employer. doma made it so he wouldn't have a green card through me. so i had to make the decision whether or not i would live my life in the country that i love or move to england and live with the person that i love. i chose the latter. january of last year we moved to the uk. while i don't regret that decision at all, this has been the most difficult and humbling period of my entire life.

>> as i understand it, you left your law firm , rented out your place, said good-bye to all of your friend and family and you end up there in london . and yours is not a situation where you're in a bubble. there are others, and in fact, profiled in a new york times article not very long ago that how many americans have done the same thing. forced to leave the united states as a result of doma .

>> and we're the lucky ones tp there are so many people who don't have england or canada or holland or country like that to o go to. and families are split apart. and you can imagine if there are children involved, that what that means. and financially, what that means. i add career i was forced to leave. i was finally getting to the place in my adult hood where i was reaching professional success and i a i arrived here. for 11 months i couldn't find work. i went on interview after interview after interview but i lacked london experience. so i was pushed down to the bottom of the ladder unfairly. this is what doma maept for me.

>> if doma is struck down, will that mean you and your partner would be married in new york, for example, and move back here?

>> you know, that's a difficult question for me to answer. obviously, there's a lot that goes into uprooting, both ways you go across the atlantic. that's a decision my partner and i would have to take after reflecting a lot. but you can't just snap your fingers and get your life back. this wasn't a blip. this was a major, major hardship and sacrifice that i've had to endure and that so many other people have had to endure.

>> brandon , thank you so much for coming on to dois cuss your life and as you point out would be make this major life decision as a result of the defensive marriage act . thank you for your time. we will keep up-to-date with you.

>> thank you.

Source: http://feeds.nbcnews.com/c/35198/f/654708/s/2a100046/l/0Lvideo0Bmsnbc0Bmsn0N0Cid0C51351342/story01.htm

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New research looks at novel ways to combat drug resistance

New research looks at novel ways to combat drug resistance [ Back to EurekAlert! ] Public release date: 27-Mar-2013
[ | E-mail | Share Share ]

Contact: Glenn Harrsis
G.Harris@soton.ac.uk
44-023-805-93212
University of Southampton

University of Southampton biological scientists are leading a major research project aimed at making drugs more effective.

They are investigating a group of proteins called 'multidrug transporters', which remove unwanted and toxic material from cells. Normally these proteins protect cells from toxins, but multidrug transporters also prevent anticancer drugs from killing cancer cells, particularly since the amount of these proteins is increased in cancer cells when they encounter such drugs. Related proteins also remove antibiotics from bacteria and remove herbicides from the plant cells of weeds leading to herbicide resistant weeds.

All cells are surrounded by a membrane made of molecules called lipids, which forms a barrier that prevents the movement of many important biological molecules into and out of the cell. Embedded in this barrier are proteins that provide the cell with the ability to take in nutrients and remove waste and toxic molecules.

Dr Malcolm East, a Reader in Biochemistry, who is leading the research with Dr Howard Barton, a Reader in Biochemistry and Molecular Biology, says: "Besides ejecting waste material, cells also remove drugs, which make them less effective as treatments. We believe that a particular group of lipids, called anionic lipids, within cell membranes play a role in controlling the biological function of certain membrane proteins. We want to know how lipids interact with proteins and how that affects their ability to transport drugs.

"Understanding these mechanisms could suggest ways of improving the effectiveness of antibiotics, anti-malarial drugs and cancer treatments and boost the action of herbicides and pesticides."

Anionic lipids in the membrane change in amount and distribution when cells respond to changes in their environment. By labelling different proteins and lipids, the scientists can determine which lipids have a closer relationship with the multidrug transporter and how it affects the drug transporting ability of the protein.

Dr Barton adds: "These studies will tell us how signals are transmitted to membrane proteins by changes in membrane lipid composition and distribution. In addition a greater understanding of how multidrug transporters are controlled by lipids, may suggest ways in which these proteins can be controlled by the use of novel drugs that would also interact with these multidrug transporters. This could help to tackle treatment failures caused by the serious problems of antibiotic resistance in bacteria and resistance to anticancer drugs seen with repeated rounds of chemotherapy. A similar approach could be taken to provide strategies for reducing the resistance seen with a whole range of important molecules, including pesticides, herbicides and anti-malarials."

Dr East and Dr Barton have won 287,000 from the Biotechnology and Biological Sciences Research Council (BBSRC) for the three-year project.

###



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


New research looks at novel ways to combat drug resistance [ Back to EurekAlert! ] Public release date: 27-Mar-2013
[ | E-mail | Share Share ]

Contact: Glenn Harrsis
G.Harris@soton.ac.uk
44-023-805-93212
University of Southampton

University of Southampton biological scientists are leading a major research project aimed at making drugs more effective.

They are investigating a group of proteins called 'multidrug transporters', which remove unwanted and toxic material from cells. Normally these proteins protect cells from toxins, but multidrug transporters also prevent anticancer drugs from killing cancer cells, particularly since the amount of these proteins is increased in cancer cells when they encounter such drugs. Related proteins also remove antibiotics from bacteria and remove herbicides from the plant cells of weeds leading to herbicide resistant weeds.

All cells are surrounded by a membrane made of molecules called lipids, which forms a barrier that prevents the movement of many important biological molecules into and out of the cell. Embedded in this barrier are proteins that provide the cell with the ability to take in nutrients and remove waste and toxic molecules.

Dr Malcolm East, a Reader in Biochemistry, who is leading the research with Dr Howard Barton, a Reader in Biochemistry and Molecular Biology, says: "Besides ejecting waste material, cells also remove drugs, which make them less effective as treatments. We believe that a particular group of lipids, called anionic lipids, within cell membranes play a role in controlling the biological function of certain membrane proteins. We want to know how lipids interact with proteins and how that affects their ability to transport drugs.

"Understanding these mechanisms could suggest ways of improving the effectiveness of antibiotics, anti-malarial drugs and cancer treatments and boost the action of herbicides and pesticides."

Anionic lipids in the membrane change in amount and distribution when cells respond to changes in their environment. By labelling different proteins and lipids, the scientists can determine which lipids have a closer relationship with the multidrug transporter and how it affects the drug transporting ability of the protein.

Dr Barton adds: "These studies will tell us how signals are transmitted to membrane proteins by changes in membrane lipid composition and distribution. In addition a greater understanding of how multidrug transporters are controlled by lipids, may suggest ways in which these proteins can be controlled by the use of novel drugs that would also interact with these multidrug transporters. This could help to tackle treatment failures caused by the serious problems of antibiotic resistance in bacteria and resistance to anticancer drugs seen with repeated rounds of chemotherapy. A similar approach could be taken to provide strategies for reducing the resistance seen with a whole range of important molecules, including pesticides, herbicides and anti-malarials."

Dr East and Dr Barton have won 287,000 from the Biotechnology and Biological Sciences Research Council (BBSRC) for the three-year project.

###



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/uos-nrl032713.php

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Mercedes-Benz introduces B-Class Electric Drive, we go eyes-on

MercedesBenz introduces BClass Electric Drive, we go eyeson

Electric Vehicle choices keep getting more compelling, and Mercedes-Benz is doing its part by unveiling the upcoming B-Class Electric Drive. The B-Class is among the smaller of MB's cars (one step up from the A-Class), fitting squarely in the MPV category. It's basically a mini-minivan. MPVs are small but big enough to be practical, and they tend to be economical. The fully electric powertrain in this 2014 model that just rolled onto the stage here at the New York International Auto Show should go a long way in that regard. Follow us after the break for more details and some photos.

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Source: http://www.engadget.com/2013/03/27/mercedes-benz-b-class-electric-drive/

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মঙ্গলবার, ২৬ মার্চ, ২০১৩

Chrome update brings improved spell checking to Windows, Linux and Chrome OS

A new stable release of Chrome is out today, bringing improved spell-checking to Google's browser. Mountain View announced the update on the Chrome Blog, explaining that it refreshed the dictionaries for all supported languages -- and adding support for Albanian, Korean and Tamil. Additionally, the "Ask Google for suggestions" feature now includes grammar checking and context-sensitive spell-checking in English, so you can expect the search giant to set you straight on the difference between "affect" and "effect." If you've added custom words to your dictionary, you'll now be able to sync them across all your devices running Chrome. Look for the browser update to roll out to Windows, Linux and Chrome OS users in the coming weeks -- Mac support is still in the works.

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Source: Google Chrome Blog

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/4Eag_kBRo5o/

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Sports Opportunities in Goose Creek | Drew Sineath

With spring in the air and warmer weather here, Goose Creek is gearing up for a fresh round of sports opportunities. With playing fields spread throughout the city and two community centers, you?ll be able to find a sport for you and for the kids in a nearby location. Let?s have some fun, Goose Creek, and get moving this spring!

Goose Creek Recreation Commission locations:

GC Community Center, 519A N. Goose Creek Blvd.

The new GC Community Center houses the administrative offices of the Recreation Sports Opportunities in Goose CreekCommission, 2 full-size gymnasiums, a fitness center, cardio-deck, walking track, climbing wall, preschool classroom and multi-purpose classroom. Sports fields.

Casey Community Center,101 Old Moncks Corner Rd.

Houses classrooms for ballet, karate, and gymnastics, plus two tennis courts.

Goose Creek?s playing fields are located:

Felkel Field Sports Complex
Located on Lucy Drive in the Beverly Hills sub-division, has 7 lighted ball fields, a concession stand and press boxes.

Dennis Park Baseball Field
Located at 351 Anita Drive in the Boulder Bluff sub-division, has one regulation size baseball field and a concession stand.

Dogwood Park Sports Complex
Located off of Liberty Hall Road, has one regulation size soccer field, one football field, concession stand and picnic area.

Eubanks Park, Old Moncks Corner Road beside the Recreation Center.
Playground, covered picnic area available for rentals, grills, basketball courts, sand volleyball courts and tennis courts nearby.

Foster Creek Park, Foster Creek Road next to Goose Creek Primary School.
Playground, picnic tables, soccer fields, concession stand

Sports offered through the Goose Creek Recreation Department

Kids:

Gymnastics ? ages 2 and up, from beginners to advancedSports Opportunities in Goose Creek

Karate ? ages 5 and up

League Baseball, Boys and Girls (ages as of 4/30/13)

  • T-Ball ages 4-5
  • Machine-Pitch, Singe A, ages 6-7
  • Modified Machine/Kid Pitch -Double AA (7 year olds must have played at one year of Single A), ages 7-8
  • Minors, ages 9-10
  • Majors, ages 11-12
  • Junior, ages 13 ? 15

League Softball, Girls (ages as of 1/1/13)

  • Machine-Pitch, ages 6-8
  • Minors, ages 9-10
  • Majors, ages 11-12
  • Jr./Sr., ages 13-16

GOOSE CREEK DIAMONDBACKS

COMPETITIVE BASEBALL & SOFTBALL

  • Competitive Travel Baseball teams for ages 10-18.
  • Competitive Travel Softball teams for ages 10-14.
  • For additional information, please contact President Ginger Collins 843-259-1099.

Football

  • Ages 6-8: Midget Flag
  • Ages 9-10: Pee Wee: Weight Limit 135 pounds
  • Ages 11-12: Small Fry: Weight Limit 150 pounds
  • Participants over the weight limit may still play in a limited capacity.
  • Middle School League: Ages 13-14: This league will travel and play other area Middle Schools.
  • All ages are as of September 1, 2012

Tennis

  • Ages 8 and up
  • Learn the basic strokes or improve your game.

Parkour -? involves running, jumping, vaulting and flipping over obstacles. That could be roofs, rails, stairs, ledges and anything else you might literally run into or climb over.

Volleyball ? middle school, grades 5 & 6

Soccer

  • Ages 4 -10; Practices will start in March, games will be played on week nights beginning in April
  • Boys & Girls, ages 4 & 5 : Tiny Tot
  • Boys & Girls, ages 6-7: Pee Wee
  • Boys & Girls, ages 8-10 Small Fry
  • These will be small sided leagues, teaching basic skills
  • All ages are as of August 1, 2013

Cheerleading ? girls, ages 6 ? 14. This program will cheer for our youth football teams.

Adults:

Basketball ? ages 18+ co-ed league

Karate ? classes are held year round

Dancing ? salsa, ballroom, Latin, shag, Irish step, belly dancing

Tennis ? improve your game or come learn the basics

Volleyball ? ages 16 and up; 8-week recreational league; at Goose Creek Community Center

Adults & Kids:

Creekers on the Run, running and walking club for ages 10 and up.

So grab your athletic shoes, Goose Creek, and I hope to see you out there playing! And if you need assistance with your real estate needs, please call Drew Sineath and Associates, we?re locals and we?d be glad to help you.

Source: http://drewsineath.com/blog/2013/03/sports-opportunities-in-goose-creek/

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Curve Appeal: Do Men Know Something About Women's Bodies ...

Curve Appeal: Do Men Know Something About Women's Bodies That Women Do Not?I?ll be the first to admit it: I am sort of a sucker for consumer-friendly psychology magazines. Publications like Psychology Today are full of articles I either enjoy reading or using as fire kindling. Or, when I am really irritated by the content, writing articles on the topic. Like this one.

The article, published in Psychology Today, is titled ?Ahead of the Curves? and the brilliant tagline? ?Men know something vital about women?s body shapes that women don?t. Plus: How big hips make wise women.?

It is six pages long and features illustrations of women who look more like playmates than the women who have the aforementioned ?big hips? and are ?wise? because of it. One of the illustrations boasts a sexy blonde wearing a pastel-pretty bra and tight briefs. She is pursing her red lips ? ready to kiss! She is rather revolting and her hips, well, they certainly are not wise.

That alone is irritating but this is the part that really makes me question my taste in literature: This lengthy article is written by two men.

Their respective names and impressive education are listed in very small font. I wondered: How can these two men possibly educate and enlighten women on their sex appeal and bodies? Well, they certainly gave it a good shot. But not good enough.

The first paragraph states that ?American males, it has been calculated, spend some $3 billion a year to gaze at women with hourglass figures, those whose small waists blossom into sinuously curvy hips.?

My first thought? Where does this ?calculation? come from? Furthermore, how does gazing at women connect to ?$3 billion a year?? They don?t explain this. Maybe men take time off work to gawk at women? Unlikely.

I have to give credit where credit is due: They do include research done by the late Deborah Sing ? 20 years ago. This is the only mention of a female contribution to the piece and does not extend past one measly paragraph which tells the eager reader: ?. . .Men all around the world. . .Prefer a similar shape.?

We are then told that when men view a curvy woman their brains respond in a similar fashion to cocaine and heroin. Hmm. That?s a strange statement with no research provided to the reader.

Even so, the following paragraph takes the cake:

Even a thin woman carries an astonishing amount of fat in her legs and hips?about a third of her body weight. Men everywhere admire the fat located here. . .Only bears ready to hibernate, penguins facing a sunless winter without food, or whales swimming in the arctic waters have fat percentages that approach those in normal, healthy, trim young women.

Well, that?s lovely! Female readers have now been compared to bears, penguins and whales. Furthermore, the word ?astonishing? used in relation to our apparent ?fat? probably does not make us smile. I am currently grimacing.

For diversity?s sake (or perhaps the editor was concerned about backlash from readers) a few paragraphs are devoted to explaining that American women are in dire need of more omega-3s.

Unfortunately, I believe more women have read this article than men. The pages are laced with bright pink script. I kid you not. Literature like this confuses both genders and, in my humble and currently sarcastic opinion, the size of my hips does not make me ?wise.? And neither did reading this article.

Reference

Lassek, W. & Gaulin, S. (2012, August). Ahead of the curves. Psychology Today, 45(4), 74-77.

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Natalie Jeanne Champagne is the author of The Third Sunrise: A Memoir of Madness. You can learn about Natalie and the book on her website at www.thethirdsunrise.com

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Catch up on other posts by NatalieJeanne Champagne (or subscribe to their feed).



????Last reviewed: By John M. Grohol, Psy.D. on 25 Mar 2013
????Published on PsychCentral.com. All rights reserved.

APA Reference
Champagne, N. (2013). Curve Appeal: Do Men Know Something About Women?s Bodies That Women Do Not?. Psych Central. Retrieved on March 26, 2013, from http://psychcentral.com/blog/archives/2013/03/25/curve-appeal-do-men-know-something-about-womens-bodies-that-women-do-not/

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Source: http://psychcentral.com/blog/archives/2013/03/25/curve-appeal-do-men-know-something-about-womens-bodies-that-women-do-not/

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